![]() In the world of neuroscience the notion of learning encompasses a wide range of events involving both biological factors and those related to the interaction between the organism and its environment at both, a biological dimension and the role of interaction between the organism and its environment. LEARNING AND GENERAL NOTIONS OF ORGANIC PLASTICITY IN THE 19TH CENTURY ![]() The present article has been divided into five sections: (1) Learning and general notions of organic plasticity in the 19th century (2) The idea of “mental” plasticity proposed by William James (1842–1910) (3) Neuronal theory and “structural” plasticity: general considerations (4) Evolutionary factors of the nervous system in Cajal’s work (5) Final considerations. However, perhaps one of the most interesting aspects of his studies was his innovative capacity to interpret the structure as being the result of evolutionary mechanisms, i.e., natural selection and his proposal that, ultimately, in relation to the histology of the nervous system, such selection might occur in the establishment of connections between cells. The sheer number of studies in favor of the neuronal theory that Cajal carried out over the course of his career was impressive. It is important to highlight that the studies in the field of neuroscience converged increasingly in the twentieth century to the point that the notion of the plastic nervous system was generally accepted as a critical mechanism for learning and memory ( Barlow, 1972, 1995 Azmitia, 2002, 2007 Fields and Stevens-Graham, 2002 DeFelipe, 2006). The notion that neuronal theory is a necessary condition to explain the plasticity of neural connections will also be explored. This paper aims to examine, at the cellular level, the notion of evolution of the nervous system presented by Santiago Ramón y Cajal (1852–1934). The overall way of thinking of academic circles in Europe in the second half of the 19th century was influenced by the theories of evolution ( Baumer, 1977), with the reach of this influence extending beyond the boundaries of biology and similar sciences.Īs a result, given the general importance placed on evolution by the academic community at the time, it follows that the study of the nervous system would be approached from an evolutionary standpoint. “ Naturalists had at the time an infinite belief in the actual existence of a straight parallel and even may be an identity between the developments of a full-grown chick from a chicken egg, for instance, and the entire species of chicks from a more primitive bird.” This idea influenced naturalistic thinking ( Gould, 2010): The relationships between the development of the organism (ontogenesis) and of the species (phylogenesis) resulted in the theory of recapitulation, which proposed that in developing from embryo to adult, animals go through stages resembling or representing successive stages in the evolution of their remote ancestors. In this early period, explanations were based on the phylogenetic evolution of organisms. An important example is the strong influence of the theory of evolution on the embryologists ( Coleman, 1983). ![]() The origins of modern neuroscience was highly influenced by the revolutionary biological thinking that arose in the second half of the 19th century with the theory of Charles Darwin (1809–1882) concerning the evolution of the species through natural selection. The present article is divided into five sections: (1) Learning and general notions of organic plasticity in the 19th century (2) The idea of “mental” plasticity proposed by James (3) Neuronal theory and “structural” plasticity: general considerations (4) Evolutionary factors of the nervous system in Cajal’s work and (5) Final considerations. This capacity would ultimately lead Cajal to the conclusion that, in relation to the histology of the nervous system, such selection occurs in the establishment of connections between cells. It is true that he carried out a large number of studies throughout his career in favor of the neuronal theory, but perhaps one of the most interesting aspects of his studies was his innovative capacity to interpret structure as being the result of evolutionary mechanisms, i.e., natural selection. Although the roots of the term “plasticity” in reference to neuroscience are not completely clear, Cajal was an important figure in the propagation and popularization of its use. Here we develop Cajal’s notion that neuronal theory is a necessary condition to explain the plasticity of neural connections. In this article we discuss the influence of William James and Charles Darwin on the thoughts of Santiago Ramón y Cajal concerning the structure, plasticity, and evolution of the nervous system at the cellular level. ![]()
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![]() ![]() The kind soul who replies to you has asked you to post the contents of your /etc/apache2/nf file. You are having some trouble with your Apache Web Server, and you have reached out to one of the many awesome forums on the net asking for some help. The grep can also be used to search and filter within individual files or multiple files. Using the –i option is a good habit of getting into unless, of course, you are trying to nail down a more specific search. ![]() The –i option is there to ignore-case, as grep is case-sensitive. Second, we piped that output to grep –i python, which simply states “go to grep and filter out and return everything with ‘ python’ in it.” Ii python3-brlapi:amd64 6.0+dfsg-4ubuntu6 amd64 Braille display access via BRLTTY - Python3 bindingsįirst, we ran dpkg –l, which lists installed *.deb packages on your system. Ii python3-blinker 1.4+dfsg1-0.3ubuntu1 all fast, simple object-to-object and broadcast signaling library Ii python3-aptdaemon.gtk3widgets 1.1.1+bzr982-0ubuntu32.3 all Python 3 GTK+ 3 widgets to run an aptdaemon client Ii python3-aptdaemon 1.1.1+bzr982-0ubuntu32.3 all Python 3 modules for the server and client of aptdaemon Ii python3-apt 2.0.0ubuntu0.20.04.8 amd64 Python 3 interface to libapt-pkg Ii python3-apport 2.20.11-0ubuntu27.24 all Python 3 library for Apport crash report handling Ii python3 3.8.2-0ubuntu2 amd64 interactive high-level object-oriented language (default python3 version) Ii python-apt-common 2.0.0ubuntu0.20.04.8 all Python interface to libapt-pkg (locales) Ii libpython3.8-stdlib:amd64 3.8.10-0ubuntu1~20.04.5 amd64 Interactive high-level object-oriented language (standard library, version 3.8) Ii libpython3.8-minimal:amd64 3.8.10-0ubuntu1~20.04.5 amd64 Minimal subset of the Python language (version 3.8) You have been scouring the web looking for tutorials, but you see that there are two different versions of Python in use, and you don’t know which version of Python is installed on Ubuntu by the installer, or if it installed any modules.įinding Files with Grep Command ii libpython3-stdlib:amd64 3.8.2-0ubuntu2 amd64 interactive high-level object-oriented language (default python3 version) Let’s say that you have just installed a fresh copy of the new Ubuntu on your machine and that you are going to give Python scripting a shot. I have found that the easiest way to get your feet wet with the grep command is to just dive right in and use some real-world examples. If for whatever reason, it is not installed on your system, you can easily install it via your package manager as shown. Grep is a powerful file pattern searcher that comes equipped on every distribution of Linux. Have you ever been confronted with the task of looking for a particular string or pattern in a file, yet have no idea where to start looking? Well then, here is grep to the rescue! ![]() ![]() ![]() Besides, Ghostery uses the leading anti-tracking technology to protect your device data from being tracked. It gives you a cleaner, faster and safer browsing experience. The Ghostery built-in ad blocker can help block advertisements from web pages to let you focus on the content you like. It is a privacy and security-related browser extension. ![]() Ghostery is another open-source and free Chrome ad blocker. 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What Is the Best Free Ad Blocker for Chrome?ĪdBlock is the best ad blocker for Chrome and used by many people. ![]() ![]() ![]() The first time I read about Personal Shopping my head filled with visions of Hollywood A-listers closing down American Apparel to buy T-shirts in peace. ![]() The more a customer knows about their hardware and software and the more specific the questions asked, the more they can help you. My only advice is to prepare well for the appointment. A Mac Genius dialing (800) APL-CARE from the store would have been a waste of time, not to mention depressing. “If that doesn’t work, bring it in and we’ll take a look,” he said.Įven though I was bounced around to three different specialists, I got a strong feeling that someone at the Apple Store could actually help me face-to-face, if not on this trip, then on the next when I had more information. This guy was in the middle of a one-on-one tutorial, but he turned around, processed my questions and offered two solid fixes for me to try at home. My first disappointment of the day came when genius Jason didn’t know the answer to my problem, but he quickly referred me to another associate who specializes in a suite of Apple’s creative software, including Final Cut. With a few minutes to wait, I walked past the “Just for Kids” area, a low table with four computers and black squishy beanbags for children, and perused the latest iPod speaker systems. My name wasn’t listed among the next 10 customers flashing across the flat screen leader board, but Jason at the Genius Bar offered to squeeze me in as soon as he could. Mac users can make appointments online with a Mac Genius, so-called know-it-alls who help solve technical problems with any Apple product. Brian thought about it for a second then admitted that I needed a genius.Īpple provides those, too. Consequently, I was using up all the memory on my MacBook Pro’s hard drive to store footage. Final Cut was telling me there were time code breaks in the video that weren’t actually there. I had been unable to import video with my external hard drive set as the scratch disk into Final Cut Pro, Apple’s professional-quality video editing software. It wasn’t by design, but my next question tested the limits of this whole Personal Shopping apparatus Apple has going. I told her I had an appointment, and she introduced me to Brian, who was patient, attentive and showed me the bells and whistles on the MacBook Air, a skinny laptop weighing fewer than three pounds. ![]() I wasn’t in the store 30 seconds before a plucky concierge asked me if I needed assistance. Two workers wore bright blue shirts, and I recognized them from the Web site as Apple concierges. “It’s the hottest store in town,” the clerk at the Clarks next door said. ![]() ![]() ![]() ![]() In 2019, the Supreme Court ruled that you must register with the U.S. The idea was that you would let the government do the work of dating the creation of the work with the federal postmark and that could provide you with enough leverage to file a lawsuit if your music was ever stolen or misused. This is where a musician emails or sends a copy of the composition or recording to themselves via certified mail, leaving the package sealed with the date clearly marked on the outside. The “poor man’s copyright” is a useless and ill-advised method for proving copyright. Does the “poor man’s music copyright” actually count as proof? Most important of all, in a groundbreaking ruling, the Supreme Court has mandated that registration with the USCO is required before you can file a lawsuit and registering early can earn you $150,000 plus attorney fees per deliberate infringement – but only if you register early on. Copyright Office entitles you to enhanced benefits. However, registering your copyrights with the U.S. This could be something as simple as writing the melody or lyrics on a piece of paper or humming into a recorder. In the strictest technical terms, you own your musical copyright the moment you capture the composition or recording in a fixed medium. Sound recordings are usually owned by artists or labels. The sound recording - which is a particular recorded version of that music and lyricsĬompositions are usually owned by songwriters and/or publishers.The composition - which is the music and lyrics.There are two types of music copyright There are two types of music copyright: You and your collaborators would then want to draft a document determining the splits (the percentage of the song each person owns), and register your copyright accordingly. If you wrote a song with one or more people, you each own a portion of that song. If you wrote a song by yourself, you alone own that composition. If you work with a label, there’s a good chance the label controls the copyright to the recording - at least for some set duration. If you create a recording yourself, or if you pay for studio time and session fees, you own that sound recording. Music copyright designates the ownership of a particular song or recording ![]() ![]() ![]() ![]() Line is an advocate for the application of AI in marketing use cases and is a firm believer in the power of brand to drive business success. She has helped early-stage startups in their journey from pre-seed to seed to series A funding and has played a pivotal role in supporting successful exits for scale-ups in hyper-growth. Fueled by her passion for tech and AI, Line transitioned to working on the client side in B2B SaaS companies such as Keatext AI, Nakisa and TrackTik. What are the topics covered as a part of the curriculumOur commitment to equip you with a 360-degree understanding of the Cloud Solutions means we cover a b. During her tenure at Bookmark (WPP Group) and Weber Shandwick (IPG Group), two of the world’s most renowned agencies in content marketing and PR, respectively, she solidified her expertise by serving high-profile clients such as IBM, Amazon, Bombardier, and Air Canada. She founded and successfully grew a digital marketing agency for 10 years, boasting 45 employees and serving local tech startups and lifestyle companies. In the ratings below, the highest rating for the show will be in red and the lowest rating for the show will be in blue each year.With 25 years of experience in marketing, Line has established herself as a leader in the industry.(Note: Individual corner ratings do not include commercial time, which regular ratings include.) Ratings listed below are the individual corner ratings of Rewind.Kim Soo-yong, Hyun Jin-young, Hwang Hye Young, Shin Ji Hong Kyung-in, Lee Eui-jung, Choi Jae-woo Hyun Jin-young, Sung Dae-hyun, Kim Jung-nam Since 2006, the program has helped countless Salesforce employees with a great idea to. In addition, for this round, Jong-kook's team had to loan money from 'Rewind Bank' due to insufficient money in their bank to make the investment. Ottawa SeptemRewind today announced the close of a USD 65 million Series B round of financing led by New York-based global private equity and venture capital firm In sight Partners to scale its efforts to provide backup and recovery solutions for the most widely used software-as-a-service (SaaS) tools for businesses. These are a few words that come to mind when I think of Salesforce Labs. On the 2nd round, the casts get to invest in the few given choices and gain their profits or loss from the investment they have previously chosen to invest.ĭuring the 3rd round, all the 3 groups had to guess which groups had the best album sales within October to December 1999 and make their investment on the group. ![]() ![]() The more difficult the questions are, the more Rewind Money they get to earn if they answer the questions correctly. The Rewind Money earned for each question will be base on the difficulty level of the questions. All the groups have to answer all the 5 questions within 10 minutes. The test consists of a total of 5 questions for the 3 groups to answer. The series aims to provide capital and resources to promising startups seeking to innovate and grow. In this episode, all the 3 groups will start from 0 Rewind Money and will earn their capital from the game called Rewind Mock Test. The Cloud 15m Series by Inovia Capital and SimpsonBetakit is an exciting new opportunity for early-stage tech startups. Cast MC Įpisodes – Team(s) that had won – Team(s) that had lost Ep. In addition, each group will also get to invest with their Rewind Money and whichever group that earns the most will be the winner. This is a new type of game show where the casts goes back in time to answer relevant questions asked by the host based on the specific year. Rewind ( Korean: 리와인드) is a South Korea variety show program that was aired on Channel A and broadcast by Channel A on Wednesdays 9.30pm KST. ![]() ![]() ![]() Pilocarpine (smaller pupil in the treated eye) Examples of glaucoma medications that can cause anisocoria include:Īpraclonidine (larger pupil in the treated eye)īrimonidine (larger pupil in the treated eye) Transdermal scopolamine patches used to treat motion sickness and nausea from chemotherapyĬertain glaucoma eye drop medications also can cause anisocoria, especially if they are used to treat glaucoma in just one eye. Selective serotonin re-uptake inhibitors (SSRIs) used to treat depression Pharmacologic anisocoria is unequal pupil size that occurs as a side effect of a medication.ĭrugs that have been identified as potential causes of pharmacologic anisocoria include: ![]() Tumors inside the eye also can cause mechanical anisocoria. Examples include:Īniridia (a complete or partial absence of the iris of one eye)Ĭoloboma (a gap in the iris present at birth, giving the pupil a distinct “keyhole” or “ cat-eye” appearance)Įctopic pupil (an inherited condition that causes displacement of the pupil and dislocation of the lens) ![]() Inflammatory conditions such as iritis or uveitisĬongenital anomalies of the iris also can be a cause of mechanical anisocoria. Causes of this type of anisocoria include:Ĭomplications of eye surgery (including cataract surgery) Mechanical anisocoria is unequal pupil sizes from damage to the iris or its supporting structures. SEE RELATED: Mydriasis: Definition and causes Mechanical anisocoria If you or a family member develop symptoms of third nerve palsy, seek medical attention immediately. Pressure on the oculomotor nerve from an aneurysm, tumor or brain hemorrhage Loss of accommodation (ability to focus on near objects) In addition to anisocoria, third nerve palsy also can cause:Ī “down and out” misalignment of the affected eye ( strabismus) Paralysis (palsy) of the oculomotor nerve causes the affected eye to have a dilated pupil, resulting in anisocoria. It also influences a muscle that controls pupil size. The third cranial nerve - also called the oculomotor nerve - controls several muscles that move the eyes and eyelids. In most cases, the cause of Adie's tonic pupil is unknown. In 80% of cases, only one eye is affected, resulting in anisocoria. Adie’s tonic pupil occurs primarily in women between the ages of 20 to 40 years. The affected pupil also reacts poorly to light. Adie’s tonic pupilĪdie’s tonic pupil is a dilated pupil caused by damage to nerve fibers that control muscles in the eye that constrict the pupil. But in some cases, no cause can be found. Horner's syndrome typically is caused by an underlying medical problem, such as a stroke, tumor or spinal cord injury. A pupil affected by Horner's syndrome generally takes 10 to 20 seconds to dilate in dim lighting or a darkened room. Normal pupils (including normal pupils that are slightly unequal in size) dilate within five seconds of room lights being dimmed. Horner's syndrome also affects how quickly the smaller pupil dilates in dim lighting. Miosis (constriction of one pupil), causing anisocoriaįacial anhidrosis (loss of sweating around the affected eye) Most people with Horner’s syndrome have these three signs: In some cases, anisocoria from iritis can remain after the iritis has been successfully treated. Your eye doctor can treat the symptoms of iritis while the underlying cause of the condition is determined and controlled. Iritis has many causes, including eye infection, underlying inflammatory diseases and trauma. Acute iritis is characterized by:Ī smaller pupil in the affected eye (anisocoria) Iritis is a form of uveitis (an inflammatory disease of the eye). Examples of conditions that cause anisocoria include: Iritis Pathologic anisocoria is different pupil sizes due to an underlying condition or disease. SEE RELATED: Small pupils: What do they mean? Pathologic anisocoria Bottom: Anisocoria with one pupil smaller than normal. Middle: Anisocoria with one pupil bigger than normal. It may be intermittent or constant, and sometimes it goes away on its own. The exact cause of simple anisocoria is unknown. The presence of simple anisocoria does not appear to be influenced by sex, age or eye color. In simple anisocoria, the difference in pupil size is usually 1 millimeter (mm) or less, and both pupils react normally to light. It’s a benign (harmless) condition that affects approximately 20% of the population. Simple anisocoria - also called essential anisocoria or physiologic anisocoria - is the most common type of anisocoria. But if it occurs suddenly, this can be a sign of a serious medical condition and you should see an eye doctor immediately.Īnisocoria is pronounced “an-eye-so-CORE-ee-ah”. In most cases, anisocoria is mild, constant and no cause for concern. One pupil may be bigger than normal, or one pupil may be smaller than normal, resulting in unequal pupils. Anisocoria is different pupil sizes in each eye. ![]() ![]() ![]() Selecting a region changes the language and/or content on. Get started right away with powerful tools that will turn your business into a well-oiled machine. ![]() That’s a lot of time that can be saved with Acrobat Sign. Laws § 42.45.140 Notary Handbook A resource for notaries that describes the State required notarial procedures. 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CraftingĬrafting is the creation of items and equipment from lower-grade materials and ingredients, resulting in items and equipment that are usually better than what you can attain otherwise. That period is called the "cooldown"-you have to wait for the ability to cool down before you can use it again. In many video games, you have to wait a while after using an ability before you can use it again. A consecutive set of moves or skills that are chained together. Some games features Clan Wars or Guild Wars wherein players can partake as a group and compete against other groups. You usually "build" your character towards a specific gameplay style or set of benefits, and the final allocation of items and skills determines your "build." Clan or GuildĪ group of players in a game, most usually in an MMORPG but has increasingly spread to other types of games, including MOBAs. BuildsĪ build is the set of equipment and/or abilities chosen when leveling up and progressing a character. When a buff comes from an ability or item, it can be temporary or permanent. Buffs can come from abilities, items, or gameplay patches. When something is buffed, it's made stronger. In some games, the Boss has its abilities buffed so that they're especially stronger than their regular versions in the game. The last character in the arcade ladder, story mode, or dungeon quests. Unlike the "advanced server" or "test realm," which exists alongside the official servers, the "beta version" is only available prior to the official release of a game. The beta version of a video game is an opt-in version that's primarily used for testing new features, verifying functionality, and providing feedback to the game developers. While some arcade modes follow a story, others just throw a random set of characters at you. Mostly used in fighting games, Arcade Mode is a game mode where you fight a succession of characters-each one tougher than the last-until you reach the Final Boss. Usually appears in the form of harmful explosions, but can also occur with heals and buffs. AOE (Area of Effect)ĪOE stands for "area of effect" and refers to spells, abilities, and effects that target all units in a given area (as opposed to targeting a singular unit). AIĪI stands for "artificial intelligence" and usually refers to computer-programmed features that interact with players, most often in the form of bots and NPCs. Some games give warnings and punishments to players for going AFK because it ruins gameplay and the enjoyment of others. AFKĪFK stands for "away from keyboard" and is the term used for players who are in the game but not doing anything. Most multiplayer games have two sets of game servers: the "official servers" with current gameplay rules and features, as well as an "advanced server" or "test realm" where new features and patches can be played before they move to the official servers. Most bots are primitively designed to track and shoot-like the bots in Counter-Strike, which have fixed movement and simplistic AI. Term for game characters not controlled by a player. Related: Why Are AAA Games So Bad? Are Video Games Getting Worse? Ugh! Bot The term "AAA" was borrowed from the US credit industry, where AAA is the highest possible rating for bonds, representing the lowest risk of failure and the most likely to succeed financially. They tend to have massive budgets for development, scope, and marketing. AAA (Triple-A)ĪAA games (pronounced "triple-A games") are those developed and distributed by major game studios and game publishers. Here are some of the most common video gaming terms you should really know. To get the most enjoyment out of gaming, it helps to know what other gamers are talking about. Old phrases fall out of usage while new jargon spreads like wildfire through communities. If you're new to the world of PC games, console games, mobile games, or even VR games, you'll come across lots of unusual terms and acronyms that may be confusing at first.Īnd even if you've been a gamer for a while, the language of gaming is constantly evolving. ![]() ![]() How Can Time Tracking Benefit Individuals and Businesses?įor individuals, effective time tracking leads to increased productivity, improved focus, and better work-life balance. By understanding where your time goes, you can identify inefficiencies, eliminate time-wasting activities, and prioritize tasks effectively. Whether you’re working on a project, attending meetings, or taking breaks, tracking your time allows you to gain valuable insights into how you allocate your resources. ![]() Time tracking refers to the process of monitoring and recording the amount of time spent on various activities throughout the day. Understanding the Importance of Time Tracking What is Time Tracking, and Why is it Important? In this comprehensive guide, we will explore the benefits of using an Excel timesheet template, provide step-by-step instructions on how to use one effectively, and offer valuable insights into common questions and concerns regarding timesheet management.Įxcel Timesheet Template: Streamline Your Time Tracking Efforts 1. An Excel timesheet template is one effective tool that can assist you in this endeavor. Whether you’re a freelancer, a small business owner, or an employee in a large corporation, keeping track of your time is essential for maximizing productivity and ensuring accurate billing or payroll. In today’s fast-paced world, efficient time management is crucial for both personal and professional success. Excel Timesheet Template: Streamline Your Time Tracking Efforts Introduction ![]() |
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